Wednesday, February 8, 2023

Antihistamin mechanism of action

 Antihistamin binds with histamin receptor and opposed to histamin receptor activity. Antihistamin that bind with histamin 1 receptor in mast cell and binds with histamin 2 receptor in gastric cell.

PPI mechanism of action

PPI inhibits Hydrogen Potassiun ion Atpase enzyme and inhibits production of hydrochloric acid from perital cell of stomach.

Hydrogen potassium atpase is also called proton pump. Because, involve in producing of positive hydrogen ion.

Friday, February 3, 2023

Antibiotic resistance

 Antibiotic resistance the capacity of any microrganism to fight agaist antibiotic. It is a survibal power development of any microorganism to survive against any specific types of antibiotic.

For example, beta lactum ring produces antibiotic is resistant when microorganism learn to produce beta lactamase enzyme to destroy beta lactum ring.

To destroy beta lactumase enzyme, some antibiotics are developed by combining with clavulanic acid. 

Cefuroxim with clavulanic acid act effectively by action and protection mechanism.

Clavulanic acid destroy beta lactamase enzyme produced by bacteria and cefuroxim destroy bacteria.

Antihistamin mechanism of action

 Antihistamin binds with histamin receptor and opposed to histamin receptor activity. Antihistamin that bind with histamin 1 receptor in mas...